JOB DESCRIPTION          

The responsibilities of this Scientist contract position are to develop and routinely employ bioanalytical methods for the qualitative analysis of endogenous small molecules/peptides in CSF, plasma, and various biological tissues using mass spectrometry in support of biomarker discovery. 

Responsibilities will also include data processing, statistical analysis, and dissemination of results to project teams in support of drug discovery and development programs. 

The ideal candidate will have a proven ability to independently design and execute experiments by (nano/micro)LC-MS/MS and/or MALDI in support of biomarker discovery programs in a fast-paced environment.

This role requires a good understanding of metabolomics and targeted/non-targeted bioanalytical techniques for the de novo analysis of endogenous analytes from complex biological samples.

The candidate will work as a member of the bioanalytical group and will independently execute experiments involving sample preparation using automated liquid handlers, data acquisition on a state of the art high resolution FT-ICR MS and data processing/statistical analysis by supervised and non-supervised classification methods (e.g. PCA/ANOVA/multivariant analyses). 

The candidate should be able develop, validate, and troubleshoot methods/instrumentation.

Other responsibilities will include electronic laboratory notebook keeping and communication of results to project teams.

Experience with independent operation of FT-ICR MS, as well as, various nano/micro LC platforms and automated liquid handlers in support of metabolomics is preferred (similar experience in proteomics acceptable).

Experience with bioinformatics and/or biostatistics is a plus.